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1.
Artigo em Inglês | MEDLINE | ID: mdl-37898892

RESUMO

The paper presents the findings of a study conducted using a mass questionnaire survey of members of young families (n = 893). The purpose of the study is to identify what problems affecting well-being are faced by members of young families. In the sample, young families are represented by two groups - families with children and families without children. It was revealed that the assessment of the significance of problems in family life is different in families with children and childless families, including the number of children in the family that affects the situation. Ratings of family problems were built according to the following criteria - self-assessment of men and women and parenting experience. It is concluded that, according to a number of criteria (both material and non-material), well-being is formed.


Assuntos
Saúde da Família , Feminino , Humanos , Masculino , Federação Russa , Poder Familiar , Nível de Saúde
2.
PNAS Nexus ; 2(8): pgad242, 2023 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-37614668

RESUMO

The Christchurch mosque attacks in 2019, committed by a radical right-wing extremist, resulted in the tragic loss of 51 lives. Following these events, there was a noticable rise in societal acceptance of Muslim minorities. Comparable transient reactions have been observed elsewhere. However, the critical questions remain: can these effects endure? Are enduring effects evident across the political spectrum? It is challenging to answer such questions because identifying long-term causal effects requires estimating unobserved attitudinal trajectories without the attacks. Here, we use six preattack waves of Muslim acceptance responses from the New Zealand Attitudes and Values Study (NZAVS) to infer missing counterfactual trajectories (NZAVS cohort 2012, N=4,865; replicated in 2013 cohort, N=7,894). We find (1) the attacks initially boosted Muslim acceptance; (2) the magnitude of the initial Muslim acceptance boost was similar across the political spectrum; (3) no changes were observed in negative control groups; and (4) two- and three-year effects varied by baseline political orientation: liberal acceptance was stable, conservative acceptance grew relative to the counterfactual trend. Overall, the attacks added five years of growth in Muslim acceptance, with no regression to preattack levels over time. Continued growth among conservatives highlights the attack's failure to divide society. These results demonstrate the utility of combining methods for causal inference with national-scale panel data to answer psychological questions of basic human concern.

3.
J Ultrasound ; 2023 Jun 15.
Artigo em Inglês | MEDLINE | ID: mdl-37318745

RESUMO

The popularity of weight training, bodybuilding and general physical conditioning has led to an increased rate of musculoskeletal injuries, such as nerve compression caused by muscle hypertrophy and, stretching of nerves peripherally. We present a case of anterior interosseous nerve (AIN) entrapment syndrome/neuropathy otherwise known as Kiloh-Nevin syndrome in a 22-year-old weightlifter. Knowledge of this injury is paramount for practitioners to increase awareness among athletes and bodybuilders.

4.
Osteoarthritis Cartilage ; 30(11): 1482-1494, 2022 11.
Artigo em Inglês | MEDLINE | ID: mdl-36030059

RESUMO

OBJECTIVE: Iron accumulation is emerging as a player in aging-related disorders due to its propensity for generating reactive oxygen species (ROS). Studies investigating the role of iron in the pathogenesis of primary osteoarthritis (OA) are limited. We designed a proof-of-principle study to determine the effect of systemic iron deficiency, via an iron deficient diet, on knee OA in an animal model. METHODS: Twelve-week-old male Hartley guinea pigs received the standard diet (n = 6) or a diet devoid of iron (n = 6) for 19-weeks. Iron levels were determined in the serum, liver, and articular cartilage. Knees were collected to assess structural changes related to OA (microcomputed tomography, histopathology). Immunohistochemistry was performed to evaluate the presence and distribution of a disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS4) and ROS-driven 4-hydroxynonenal (4-HNE)-induced protein adducts. Transcript expression was also assessed. RESULTS: Relative to control animals, an iron deficient diet reduced the concentration of this mineral in serum, liver, and articular cartilage. Iron deficient animals had lower histologic OA scores; decreased subchondral bone mineral density was also noted. This reduction in knee joint pathology was accompanied by a decrease in: ADAMTS4 in synovium; and 4-HNE protein adducts from lipid peroxidation in both the menisci and articular cartilage of iron deficient animals. Expression of iron-related genes in these tissues was also altered in treated animals. CONCLUSIONS: Results from this study suggest that systemic iron levels may play a role in knee OA pathogenesis, with a short-term deficit in dietary iron reducing the severity of knee cartilage lesions.


Assuntos
Cartilagem Articular , Osteoartrite do Joelho , Cobaias , Masculino , Animais , Espécies Reativas de Oxigênio/metabolismo , Microtomografia por Raio-X , Ferro da Dieta/metabolismo , Ferro/metabolismo , Desintegrinas/metabolismo , Articulação do Joelho/metabolismo , Cartilagem Articular/patologia , Osteoartrite do Joelho/patologia , Trombospondinas , Dieta
5.
Psychophysiology ; 59(11): e14110, 2022 11.
Artigo em Inglês | MEDLINE | ID: mdl-35671400

RESUMO

Brain Fingerprinting (BFP) is an electroencephalogram-based system used to detect knowledge, or absence of knowledge of a real-life incident (e.g., a crime) in a person's memory. With the help of BFP, a potential crime suspect can be classified as possessing crime-related information (Information-Present), not possessing crime-related information (Information-Absent), or Indeterminate (BFP unable to classify a subject). In the lab setting, we compare the ground-truth of a subject (i.e., real-life involvement in an incident) against their classification based on BFP testing. We report two studies: replication of BFP with university students (Study 1) and replication of BFP with parolees (Study 2). In Study 1, we tested 31 subjects (24 females, seven males, mean age = 21.3) on either their own or another subject's real-life incident. BFP correctly classified nine Information-Present and 18 Information-Absent subjects, but with one false positive and three exclusions. In Study 2, we tested 17 male parolees (mean age = 47.5) on their own or another parolee's crime incident. BFP correctly classified two Information-Present and six Information-Absent subjects. However, there was also one false positive classification and three Indeterminates. Additionally, we identified three subjects who could not complete the BFP testing and two exclusions. We posit that BFP is not yet at a stage to be considered a robust and accurate crime-detection tool as claimed in former articles. Nevertheless, after addressing the limitations, BFP has considerable potential as an information detection tool in forensic investigations, especially for detecting idiosyncratic crime-relevant knowledge in a perpetrator, in addition to helping to confirm the accuracy of a suspect's claim of innocence.


Assuntos
Detecção de Mentiras , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Encéfalo , Crime , Eletroencefalografia/métodos
6.
Sci Rep ; 12(1): 1620, 2022 01 31.
Artigo em Inglês | MEDLINE | ID: mdl-35102221

RESUMO

The Christchurch mosque shootings on March 15th, 2019 was the deadliest incident of mass violence in New Zealand for over a century. The present study investigated the psychological impact of these terrorist attacks targeting a specific minority community on the psychological functioning of the wider New Zealand population by examining changes in terrorism anxiety, sense of community, psychological distress, and wellbeing. Data from the New Zealand Attitudes and Values Survey (N = 47,951; age range 18-99 years, M = 48.59, SD = 13.86; 62% female) collected across a year, including approximately 6 months following the terrorist attack, was used. Regression discontinuity analyses found a statistically significant increase in terrorism anxiety and sense of community following the attacks, yet counterintuitively, no significant change in psychological distress or wellbeing. These findings provide unique insight into the psychological implications of politically motivated violence for the wider population when terrorism is directed toward a specific minority group.

9.
Eye (Lond) ; 31(8): 1191-1198, 2017 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-28387764

RESUMO

PurposeTo characterize the optic nerve head (ONH) structure in patients with non-arteritic anterior ischemic optic neuropathy (NAION) compared to healthy control subjects using spectral domain optical coherence tomography (SD-OCT) via the enhanced depth imaging method.MethodsIn this prospective, cross-sectional, comparative study, we assessed 66 eyes of 33 patients with unilateral NAION and 31 eyes of 31 healthy normal subjects in an academic institution. The peripapillary nerve fiber layer thickness, disc area, and quantitative parameters of the ONH structures, including the Bruch's membrane opening (BMO) area, anterior laminar depth, and prelaminar thickness and depth were compared between the three groups.ResultsLinear mixed model analysis after adjusting for age, sex, and axial length showed that the BMO area was similar in eyes with NAION (1.89±0.33 mm2), their fellow eyes (1.85±0.35 mm2), and control eyes (1.88±0.37 mm2; all P>0.99). Anterior laminar depth was also similar in the three groups. The mean prelaminar tissue thickness of the NAION eyes was 445±176 µm, which was thinner than the prelaminar tissue of their unaffected fellow eyes (mean, 539±227 µm, P=0.004), but both were thicker than the prelaminar tissue of the normal subjects (mean 243±145 µm, P=0.001 and P<0.001, respectively).ConclusionsThe thick prelaminar thickness is associated with unilateral NAION in the affected and unaffected eyes.


Assuntos
Disco Óptico/patologia , Neuropatia Óptica Isquêmica/patologia , Adulto , Idoso , Lâmina Basilar da Corioide/patologia , Estudos de Casos e Controles , Estudos Transversais , Feminino , Humanos , Modelos Lineares , Masculino , Pessoa de Meia-Idade , Fibras Nervosas/patologia , Estudos Prospectivos , Células Ganglionares da Retina/patologia , Tomografia de Coerência Óptica/métodos , Acuidade Visual , Campos Visuais
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